Meningeal T cells function in the central nervous system homeostasis and neurodegenerative diseases

Recently, a rising interest is given to neuroimmune communication in physiological and neuropathological conditions. Meningeal immunity complex immune environment housing different types of cells. Here, we focus on meningeal T cells, possibly the most explored aspect neuro-immune cell interactions. Emerging data have shown that cells play crucial role pathogenesis several neurodegenerative disorders, including multiple sclerosis, Alzheimer’s, Parkinson’s, Huntington’s diseases. This review highlights how may contribute surveillance central nervous system (CNS) regulate neurobehavioral functions through secretion cytokines. Overall, this assesses recent knowledge their effects CNS functioning both health disease conditions underlying mechanisms.